个人简介
教授、博士生导师。
海南大学bob体育副院长,海南省海洋生物活性物质与生物制品工程研究中心主任。海南省领军人才。
工作经历
先后在中国科学院海洋所、中国科学院烟台海岸带研究所、中国科学院青岛生物能源与过程研究所、加州大学伯克利分校、天津大学和海南大学学习工作。
社会兼职
科技部、教育部、基金委和多个省科技厅评审专家。
研究兴趣
以建立藻源生物活性物质与生物制品产业体系为目标,在热带海洋生物活性物质开发、合成生物学体系建立和海洋生物制品生产体系构建方面开展研究。
主持国家重点研发计划政府间合作重点项目、国家重点研发计划课题、国家十三五海洋经济产业体系协同创新重点项目、国家自然科学基金等。参与泰山学者创新团队项目、中国科学院对外合作重点项目(中国-荷兰)、国家自然科学基金重大国际合作项目(中国-美国)、中国科学院太阳能行动计划、美国能源部基础能源科学项目等。
Functional genomics and trait optimization have been the underlying theme throughout research career of Yandu LU. He works on microalgae but the general concepts and many of the mechanisms are common to all parts of the tree of life. To begin with he focused on individual genes but advanced technology and computing now allows analysis of complex gene networks. We can now begin to address the question of emergent properties in which cells and organisms are more than the simple sum of their parts so that molecular biology is truly‘biology’. Yandu LU has become interested in synthetic biology - the application of genome editing to explain nature and improve nature. Over the years, the context of his interest in gene regulation, enzyme characterization, trait optimization, and value-added compound production has involved biosynthetic pathway, photosynthesis, stress response, and now artificial photosynthetic cells. Please find more details in http://www.scbioengineering.com/content/yandu-lu.
国内外合作代表性成果 (通讯或第一作者)
以第一作者或通讯作者论文发表于Nature Communications、Advanced Science、JACS、Molecular Plants、Trends in Microbiology、Trends in Plant Science等;授权发明专利20项。
1. Synergy between microalgae and microbiome in polluted waters. (2023) Trends in Microbiology 31(1) 9-21 (指导外籍博后针对藻际圈发表综述性论文) (IF= 18.23)
2. Engineering a marine microalga Chlorella sp. as the cell factory (2023) Biotechnology for Biofuels and Bioproducts 10.1186/s13068-023-02384-2 (联合泰国KMUTT开发了热带小球藻遗传操作体系) (IF= 7.1)
3. A widespread sterol methyltransferase participates in the biosynthesis of both C4α- and C4β-methyl sterols. (2022) Journal of the American Chemical Society 10.1021/jacs.2c01401 (联合美国MIT、澳大利亚CSIRO、同济大学海洋地质国家重点实验室珊瑚共生虫黄藻中发现了一种新型的甾体化合物代谢机制) (IF= 16.383)
4. The balancing act in photosynthetic efficiency and protection of an ancient light harvesting protein of photosystem I. (2021) Nature Communications 10.1038/s41467-021-20967-1 (联合美国劳伦斯伯克利国家实验室、加州大学伯克利分校等在海洋微藻中发现了一种崭新的“光利用”与“光损伤”平衡的调控机制) (IF= 17.694)
5. Sustainable development of microalgal biotechnology in coastal zone for aquaculture and food. Science of the Total Environment (2021) in press (联合中科院海岸带所、绿量微藻生物技术有限公司、中科院青岛生物能源所和荷兰瓦格宁根大学,完成了代表性热带工业藻种从选育-实验室验证-室内模拟-户外小规模培养-中试-户外工业化生产全生命体系评价) (IF= 10.753)
6. Microalgal engineering: the transition from empirical design to programmable cells. Critical Reviews in Biotechnology (2021) 10.1080/07388551.2021.1917507 (联合加州大学伯克利分校和马里兰大学评价了微藻为底盘的合成生物学发展现状与趋势) (IF= 9.062)
7. Isolation of a novel strain of Cyanobacterium sp. with good adaptation to extreme alkalinity and high polysaccharide yield. Journal of Oceanology and Limnology (2021) 10.1007/s00343-020-0113-7 (联合中科院南海所向文洲研究员,筛选获得了一株高耐碱、高产多糖的蓝藻,评价了其生产特性) (IF= 1.554)
8. Characterization and engineering of a dual-function diacylglycerol acyltransferase in the oleaginous marine diatom Phaeodactylum tricornutum. Biotechnology for Biofuels. (2018)http://doi.org/10.1186/s13068-018-1029-8 (联合中科院烟台海岸带所秦松研究员、崔玉琳副研究员,构建了高产蜡脂的三角褐指藻工程细胞) (IF= 7.67)
9. Producing designer oils in industrial microalgae by rational modulation of co-evolving type-2 diacylglycerol acyltransferases. (2017) Molecular Plant. 10.1016/j.molp.2017.10.011 (中科院青岛生物能源所徐健研究员牵头、联合北京大学、中科院水生所和美国马里兰大学,通过理想设计生产出了饱和度“定制化”的藻油,证明藻基产品开发的可控性与可塑性) (IF= 21.949)
10. Improved growth of bait microalgae Isochrysis and aquacultural wastewater treatment with mixotrophic culture. (2022) Bioprocess and Biosystems Engineering, 45(3):589-597. 10.1007/s00449-021-02681-w. (联合浙江海洋大学严小军教授、宁波大学程鹏飞教授开发了一种饵料微藻及其混养培养工艺) (IF= 3.434)
招生专业
博士后:有天然产物化学、代谢通路的设计与合成、海洋药物与生物资源、生物制品开发、分析化学背景的优先考虑;
博士生:生物学、食品科学与工程;
硕士生:海洋生物学、渔业发展;
联系方式
电话:+86-898-66257612
邮箱: ydlu@chi-m.com
通讯地址:海南大学bob体育, 邮编570228